has_part has part has_part has disposition at some time attenuated disposition Brucella ntrY mutant B. abortus 2308 ntrY mutant PMID: 10678941 The gene ntrY from the strain Brucella melitensis biovar Abortus 2308 is a virulence gene. NCBIGene: 3788818 Information about the mutated molecule: MUTATION: The NtrY protein is a sensor of an ntr-related regulon which may be part of the glnALG operon. This mutant has a weakly attenuated phenotype (reduction of 1.2 log units versus the wild type at 48 h postinfection) which could be explained by a pleiotropic effect on the ntr regulon, since the ntrC mutant did not show such a phenotype [Ref6484:Foulongne et al., 2000]. A mutant of strain Brucella melitensis biovar Abortus 2308 that lacks an intact gene ntrY. YH UniProtKB accession: Q2YPW5 ntrY PAS domain:ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal:Bacterial sensor prot...