has_part has part has_part has disposition at some time attenuated disposition Brucella omp10 mutant B. abortus 2308 omp10 mutant UniProtKB accession: Q2YIP8 Information about the mutated molecule: SUBCELLULAR LOCATION: Outer membrane PMID: lipid-anchor(Swiss-Prot: P0A3N9). MISCELLANEOUS: Elicits an immune response in B.melitensis-infected sheep but not in B.abortus-infected cattle(Swiss-Prot: P0A3N9). SIMILARITY: Belongs to the rhizobiaceae omp10 lipoprotein family(Swiss-Prot: P0A3N9). MUTATION: Omp10 is an immunoreactive outer membrane lipoprotein. The omp10 mutant was dramatically attenuated for survival in mice and was defective for growth in minimal medium but was not impaired in intracellular growth in vitro, nor does it display clear modification of the outer membrane properties [Ref6473:Tibor et al., 2002]. The gene omp10 from the strain Brucella melitensis biovar Abortus 2308 is a virulence gene. YH A mutant of strain Brucella melitensis biovar Abortus 2308 that lacks an intact gene omp10. NCBIGene: 3828036 omp10 lipoprotein Omp10