bearer of at some time only_in_taxon Brucella virulence factor disposition Brucella melitensis bv. 1 str. 16M BMEI0135 protein OUTER MEMBRANE LIPOPROTEIN PMID: lipid-anchor(Swiss-Prot: P0A3P2). MISCELLANEOUS: Elicits an immune response in humans, mice, sheep and goats infected with B.melitensis or B.abortus, but not in B.abortus-infected cattle(Swiss-Prot: P0A3P2). SIMILARITY: Belongs to the rhizobiaceae omp19 lipoprotein family(Swiss-Prot: P0A3P2). MUTATION: Omp19 is an immunoreactive outer membrane lipoprotein. Significantly fewer brucellae were recovered from the spleens of mice infected with the omp19 mutant than from those of mice infected with the parent strain at 4 and 8 weeks postinfection. The omp19 mutant exhibited an increase in sensitivity to the polycation polymyxin B and to sodium deoxycholate. These results indicate that inactivation of the omp19 gene alters the outer membrane properties of B abortus [Ref6473:Tibor et al., 2002]. This protein is a Brucella virulence factor. SUBCELLULAR LOCATION: Outer membrane NCBIProteinGI: 17986419 UniProtKB: PR:P0A3P1 LocusTag: BMEI0135 Molecule Role Annotation: SUBCELLULAR LOCATION: Outer membrane Gene name: omp19 NCBIProteinAccess:NP_539053.1 NCBIGene: 1195847