bearer of at some time only_in_taxon Brucella virulence factor disposition Brucella melitensis biovar Abortus 2308 purH protein bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase UniProtKB: PR:Q2YLH0 NCBIProteinAccess:YP_415170.1 LocusTag: BAB1_1824 Gene name: purH This protein is a Brucella virulence factor. CATALYTIC ACTIVITY: 10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(Swiss-Prot: P67540). CATALYTIC ACTIVITY: IMP + H(2)O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(Swiss-Prot: P67540). PATHWAY: Nucleotide biosynthesis Molecule Role Annotation: CATALYTIC ACTIVITY: 10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(Swiss-Prot: P67540). CATALYTIC ACTIVITY: IMP + H(2)O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(Swiss-Prot: P67540). PATHWAY: Nucleotide biosynthesis NCBIProteinGI: 82700596 NCBIGene: 3788876 PMID: IMP biosynthesis