bearer of at some time only_in_taxon Brucella virulence factor disposition Brucella melitensis biovar Abortus 2308 hisD protein histidinol dehydrogenase Gene name: hisD NCBIProteinGI: 82699185 UniProtKB: PR:Q2YPB8 NCBIProteinAccess:YP_413759.1 This protein is a Brucella virulence factor. FUNCTION: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine (By similarity)(Swiss-Prot: Q8G2R2). CATALYTIC ACTIVITY: L-histidinol + 2 NAD(+) = L-histidine + 2 NADH(Swiss-Prot: Q8G2R2). COFACTOR: Binds 1 zinc ion per subunit (By similarity)(Swiss-Prot: Q8G2R2). PATHWAY: Amino-acid biosynthesis NCBIGene: 3788752 PMID: L-histidine biosynthesis Molecule Role Annotation: FUNCTION: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine (By similarity)(Swiss-Prot: Q8G2R2). CATALYTIC ACTIVITY: L-histidinol + 2 NAD(+) = L-histidine + 2 NADH(Swiss-Prot: Q8G2R2). COFACTOR: Binds 1 zinc ion per subunit (By similarity)(Swiss-Prot: Q8G2R2). PATHWAY: Amino-acid biosynthesis LocusTag: BAB1_0285