bearer of at some time only_in_taxon Brucella virulence factor disposition Brucella suis 1330 purE protein phosphoribosylaminoimidazole carboxylase, catalytic subunit NCBIProteinGI: 23502601 NCBIProteinAccess:NP_698728.1 Gene name: purE NCBIGene: 1167437 PMID: IMP biosynthesis Molecule Role Annotation: FUNCTION: This subunit can alone transform AIR to CAIR, but in association with purK, which possesses an ATPase activity, an enzyme complex is produced which is capable of converting AIR to CAIR efficiently under physiological condition (By similarity)(Swiss-Prot: Q8FYW3). CATALYTIC ACTIVITY: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2)(Swiss-Prot: Q8FYW3). PATHWAY: Nucleotide biosynthesis LocusTag: BR1744 UniProtKB: PR:Q8FYW3 This protein is a Brucella virulence factor. FUNCTION: This subunit can alone transform AIR to CAIR, but in association with purK, which possesses an ATPase activity, an enzyme complex is produced which is capable of converting AIR to CAIR efficiently under physiological condition (By similarity)(Swiss-Prot: Q8FYW3). CATALYTIC ACTIVITY: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2)(Swiss-Prot: Q8FYW3). PATHWAY: Nucleotide biosynthesis