bearer of at some time only_in_taxon Brucella virulence factor disposition Brucella melitensis bv. 1 str. 16M BMEII1124 protein 6-phosphogluconate dehydrogenase UniProtKB: PR:Q8YAX7 LocusTag: BMEII1124 This protein is a Brucella virulence factor. MUTATION: gnd is involved in pentose phosphate pathway. It is essential for intracellular growth inside HeLa cells as shown by its Brucella suis miniTn5Km2 transposon mutation analysis. The mutant is attenuated in the mouse model [Ref6469:Kim et al., 2003]. NCBIProteinGI: 17989469 NCBIGene: 1198896 Gene name: gnd NCBIProteinAccess:NP_542102.1 Molecule Role Annotation: MUTATION: gnd is involved in pentose phosphate pathway. It is essential for intracellular growth inside HeLa cells as shown by its Brucella suis miniTn5Km2 transposon mutation analysis. The mutant is attenuated in the mouse model [Ref6469:Kim et al., 2003]. PMID: 12761078