bearer of at some time only_in_taxon Brucella virulence factor disposition Brucella melitensis bv. 1 str. 16M BMEI0516 protein aspartate aminotransferase NCBIProteinAccess:NP_539433.1 NCBIGene: 1196227 Gene name: aspC LocusTag: BMEI0516 NCBIProteinGI: 17986799 UniProtKB: PR:Q8YIC8 Molecule Role Annotation: MUTATION: aspC encodes for an aminotransferase. B.abortus aspC mutant obtained from randomized miniTn5Km2 transposon mutagenesis showed decreased intracellular survival inside HeLa cells. So B. abortus aspC gene is essential for HeLa cell intracellular growth [Ref6469:Kim et al., 2003]. PMID: 12761078 This protein is a Brucella virulence factor. MUTATION: aspC encodes for an aminotransferase. B.abortus aspC mutant obtained from randomized miniTn5Km2 transposon mutagenesis showed decreased intracellular survival inside HeLa cells. So B. abortus aspC gene is essential for HeLa cell intracellular growth [Ref6469:Kim et al., 2003].