has_part
has part
has_part
has disposition at some time
attenuated disposition
Brucella ugpB mutant
B. abortus 2308 ugpB mutant
A mutant of strain Brucella melitensis biovar Abortus 2308 that lacks an intact gene ugpB.
UniProtKB accession: Q2YKR5
YH
The gene ugpB from the strain Brucella melitensis biovar Abortus 2308 is a virulence gene.
PMID: 16817909
NCBIGene: 3827694
Information about the mutated molecule: MUTATION: B suis ugpB mutant does not contain SP41 protein. Mutants lacking SP41 production are less invasive, but proliferate in HeLa cells. An isogenic DeltaugpB mutant showed a significant inhibitory effect on Brucella adherence and invasion of human cultured epithelial cells and this effect could be reversed by restoration of the ugpB on a plasmid. [Ref6479:Castañeda-Roldán et al., 2006].
ugpB
Bacterial extracellular solute-binding protein, family 1