falciparum malaria severe malaria 2008-05-16T02:06:32Z A form of falciparum malaria where Plasmodium falciparum infections are complicated by serious organ failures or abnormalities in the patient's blood or metabolism. It is characterized by the presence of one or more of prostration, impaired consciousness, respiratory distress (acidotic breathing), multiple convulsions, circulatory collapse, pulmonary edema, abnormal bleeding, jaundice, hemoglobinuria, and sever anemia. The essential pathological feature of severe falciparum malaria is sequestration of erythrocytes containing mature forms of the parasite in the deep vascular beds of vital organs. IDOMAL:0000271 IDOMAL:0000271 idomal_namespace louis