Small GTPase hydrolysis signaling Ras-GTP hydrolysis signaling IEV:0000703 event Negative regulation of Ras mediated signaling Negative regulation of PDGF signaling pathway (through Grb2, Sos, Ras and Erk cascade) Negative regulation of PDGF signaling pathway (through Grb2, Sos, Ras, PI3K, AKT and IKK-NF-kappaB cascade) Negative regulation of RTK signaling pathway (through Grb2, Sos, Ras, RalGDS, Ral, RalBP1 and Rac-GTP hydrolysis signaling) Negative regulation of RTK signaling pathway (through Grb2, Sos, Ras, RalGDS, Ral and PLD)