part of Dissociation in cytosol Raf activation signaling (through RKIP) Dissociation of RKIP and Raf1 in cytosol IEV:0001358 IMR:0100355 Protein kinase C (PKC) regulates activation of the Raf-1 signaling cascade by growth factors, but the mechanism by which this occurs has not been elucidated. Here we report that one mechanism involves dissociation of Raf kinase inhibitory protein (RKIP) from Raf-1. PubMed:12551925 UniProt:P30086 event