Polyketide biosynthesis GO:0030639 IEV:0001559 The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty-acid biosynthesis but without the intermediate reductive steps. event polyketide anabolism polyketide biosynthetic process polyketide formation polyketide synthesis Carboxylic acid metabolism