acyl-CoA dehydrogenase GO:0003995 IMR:0000999 There are nine known members in the acyl-CoA dehydrogenase (ACAD) family. Five members of the ACAD family are involved in fatty acid beta-oxidation; these are short, medium, long and very long chain acyl-CoA dehydrogenase (SCAD, MCAD, LCAD and VLCAD1, resepctively), and ACAD-9 (VLCAD2). The four other members are involved in amino acid oxidation pathways; they are iso(3)valeryl-CoA dehydrogenase (i3VD) for leucine, iso(2)valeryl-CoA dehydrogenase (i2VD, also known as short/branched chain acyl-CoA dehydrogenase or 2-methylbutyryl-CoA dehydrogenase) for isoleucine, isobutyryl-CoA dehydrogenase (iBD) for valine, and glutaryl-CoA dehydrogenase (GD) for lysine and tryptophan. molecule_role dehydrogenase