has characteristic tau-leaping method adaptive explicit-implicit tau-leaping method http://identifiers.org/doi/10.1063/1.2745299 Modification of the original tau-selection strategy [http://identifiers.org/biomodels.kisao/KISAO_0000040], designed for explicit tau-leaping, is modified to apply to implicit tau-leaping, allowing for longer steps when the system is stiff. Further, an adaptive strategy is proposed that identifies stiffness and automatically chooses between the explicit and the (new) implicit tau-selection methods to achieve better efficiency. spatial description explicit method type implicit method type