has characteristic is hybrid of hybrid method ordinary differential equation problem flux balance analysis dynamic flux balance analysis 2017-09-12 http://identifiers.org/doi/10.1186/s12859-014-0409-8 true AZ DFBA Dynamic flux balance analysis (DFBA) enables the simulation of dynamic biological systems by assuming organisms reach steady state rapidly in response to changes in the extracellular environment. DFBA couples flux balance analysis (FBA) [http://identifiers.org/biomodels.kisao/KISAO_0000437] model approaches with dynamic model approaches. Ticket 32 flux balance method flux balance problem