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    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000521 -->

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        <rdfs:label xml:lang="en">simulated annealing parameter</rdfs:label>
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    <!-- http://www.biomodels.net/kisao/KISAO#KISAO_0000522 -->

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        <rdfs:label xml:lang="en">start temperature</rdfs:label>
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        <skos:definition xml:lang="en">Initial temperature of the system. The higher the temperature, the larger the probability that a global optimum is found. Note that the temperature should be very high in the beginning of the method (the system should be above the &quot;melting&quot; temperature). This value has the same units as the objective function, so what represents &quot;high&quot; is different from problem to problem.</skos:definition>
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