has parameter flux variability analysis 2020-08-11 http://identifiers.org/biosimulators/cobrapy http://identifiers.org/doi/10.1016/j.ymben.2003.09.002 AZ FVA Method for determining the minimum and maximum flux of each reaction that satisfies the flux constraints of the flux balance analysis (FBA) [http://identifiers.org/biomodels.kisao/KISAO_0000437] model. parallelism fraction of optimum loopless reactions nested algorithm flux balance method general steady state method