linear MOMA 2020-10-29 http://identifiers.org/biosimulators/cobratoolbox http://identifiers.org/biosimulators/optflux http://identifiers.org/doi/10.1038/ng.846 JRK Linear Minimization of Metabolic Adjustment Linear minimization of metabolic adjustment (MOMA) is an extension of FBA for the prediction of flux distributions in gene knockouts. Linear MOMA employs linear programming to identify the closest point (in terms of its L1 norm) in the permissible flux space of the knockout to the wild-type flux vector by solving the optimization problem Min sum(|fluxAi - fluxBi|) linear minimization of metabolic adjustment MOMA