has parameter
quadratic MOMA
2020-10-29
http://identifiers.org/biosimulators/cobratoolbox
http://identifiers.org/biosimulators/optflux
http://identifiers.org/biosimulators/raven
http://identifiers.org/doi/10.1073/pnas.232349399
JRK
MOMA
Minimization of metabolic adjustment (MOMA) is an extension of FBA for the prediction of flux distributions in gene knockouts. MOMA employs quadratic programming to identify the closest point (in terms of its Euclidean distance) in the permissible flux space of the knockout to the wild-type flux vector by solving the optimization problem
Min sum((fluxAi - fluxBi)^2) + sum(fluxAi)^(fluxMinimizationWeight) + sum(fluxBi)^(fluxMinimizationWeight)
Quadratic Minimization of Metabolic Adjustment
minimization of metabolic adjustment
quadratic minimization of metabolic adjustment
flux minimization weight
linear MOMA
MOMA