linear MOMA
2020-10-29
http://identifiers.org/biosimulators/cobratoolbox
http://identifiers.org/biosimulators/optflux
http://identifiers.org/doi/10.1038/ng.846
JRK
Linear Minimization of Metabolic Adjustment
Linear minimization of metabolic adjustment (MOMA) is an extension of FBA for the prediction of flux distributions in gene knockouts. Linear MOMA employs linear programming to identify the closest point (in terms of its L1 norm) in the permissible flux space of the knockout to the wild-type flux vector by solving the optimization problem
Min sum(|fluxAi - fluxBi|)
linear minimization of metabolic adjustment
MOMA