Coma [Disease/Finding] A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION. D003128 C1816 Coma N0000000819 M0004841 988251 Coma 371632003 C0009421 Comatose Unconsciousness [Disease/Finding]