Kidney Failure, Chronic [Disease/Finding] 90688005 Kidney Failure, Chronic End-Stage Renal Disease D007676 Renal Disease, End-Stage N0000001750 ESRD M0012016 C3678 End-Stage Kidney Disease Renal Failure, End-Stage C0022661 Kidney Failure, Chronic The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION. Renal Failure, Chronic Chronic Kidney Failure 988914 Renal Insufficiency, Chronic [Disease/Finding]