capable of capable_of capable of elicited macrophage inflammatory macrophage classically activated macrophage An elicited macrophage that is recruited into the tissues in response to injury and infection as part of an inflammatory response, expresses high levels of pro-inflammatory cytokines, ROS and NO, and shows potent microbicidal activity. Markers: Express: TNFa, IL1b, IL6, iNOS, NADPH-oxidase; produce: reactive oxygen species, nitric oxide; role or process: immune, inflammation (inflammatory response). M1 macrophage interleukin-1 beta production interleukin-6 production tumor necrosis factor production superoxide anion generation defense response to bacterium nitric-oxide synthase biosynthetic process