has_part has part has part lacks_plasma_membrane_part participates in participates_in participates in lacks_plasma_membrane_part small pre-B-II cell small pre-BII cell A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes. Small pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-negative, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive. cell pre-B-II cell B cell receptor complex pre-B cell receptor complex immunoglobulin light chain V-J recombination V(D)J recombination-activating protein 1 V(D)J recombination-activating protein 2