<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/KTAO?iri=http://purl.obolibrary.org/obo/CMO_0001658"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns2="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://www.geneontology.org/formats/oboInOWL#">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/creation_date"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOWL#xref"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000412"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/def"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOWL#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/created_by"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CMO_0001658 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CMO_0001658">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">logarithm of the concentration of angiotensin II at which the force of blood vessel contraction is half the maximum value (Log EC50)</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CMO_0001659"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CMO_0002465"/>
        <ns2:creation_date rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2013-06-20T14:24:41Z</ns2:creation_date>
        <ns2:def rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A calculated value for logarithm of the concentration of angiotensin II (AngII), the octapeptide, Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, that is derived from angiotensinogen and acts as a powerful vasopressor and stimulator of aldosterone secretion, at which the energy produced by the active reduction in the diameter of a blood vessel in response to the application of AngII is halfway between the baseline value and the highest achievable value of such AngII-induced contractile energy. The logarithm of the concentration is the exponent indicating the power to which 10 must be raised to obtain that concentration value.</ns2:def>
        <ns3:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Ang2 Log half maximal effective concentration</ns3:hasRelatedSynonym>
        <ns3:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AngII Log half maximal effective concentration</ns3:hasRelatedSynonym>
        <ns2:created_by rdf:datatype="http://www.w3.org/2001/XMLSchema#string">JSmith</ns2:created_by>
        <ns3:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">angiotensin 2 Log half maximal effective concentration</ns3:hasRelatedSynonym>
        <ns3:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">angiotensin II Log half maximal effective concentration (EC50)</ns3:hasRelatedSynonym>
        <ns3:xref rdf:resource="http://purl.obolibrary.org/obo/CHEBI_48432"/>
        <ns2:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/cmo.owl"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CMO_0001659 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CMO_0001659">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">angiotensin II response/sensitivity measurement</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CMO_0002465 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CMO_0002465">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">logarithm of the concentration of vasoconstrictor at which the force of blood vessel contraction is half the maximum value (Log EC50)</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



