has_participant has participant has participant response to hypoxia Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. GO:0001666 Note that this term should not be confused with 'response to anoxia ; GO:0034059'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%. biological_process response to hypoxic stress response to intermittent hypoxia response to lowered oxygen tension response to sustained hypoxia response to stress response to decreased oxygen levels CD38 CLDN3 CRYAB HSD11B2 NOS1 PLAT VCAM1 POSTN