has_participant has participant has participant protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity ATP:protein-L-tyrosine O-phosphotransferase (receptor-type) activity ATP:protein-tyrosine O-phosphotransferase activity Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. Drosophila Eph kinase activity EC:2.7.10.1 GO:0004714 MetaCyc:2.7.10.1-RXN RHEA:10596 Reactome:R-HSA-166544 Reactome:R-HSA-167019 Reactome:R-HSA-167683 Reactome:R-HSA-169905 Reactome:R-HSA-177933 Reactome:R-HSA-198295 Reactome:R-HSA-6784324 Reactome:R-HSA-74711 Reactome:R-HSA-74715 Reactome:R-HSA-74742 Reactome:R-HSA-8852552 Reactome:R-HSA-8853792 Reactome:R-HSA-8950269 Reactome:R-HSA-8950340 Reactome:R-HSA-8950354 Reactome:R-HSA-8950364 Reactome:R-HSA-8950405 Reactome:R-HSA-8950423 Reactome:R-HSA-8950453 Reactome:R-HSA-8950485 Reactome:R-HSA-8950537 Reactome:R-HSA-8950591 Reactome:R-HSA-8950757 Reactome:R-HSA-8982163 Reactome:R-HSA-8983300 Reactome:R-HSA-8983309 Reactome:R-HSA-8983371 Reactome:R-HSA-8983424 Reactome:R-HSA-8986985 Reactome:R-HSA-8986994 Reactome:R-HSA-8986995 Reactome:R-HSA-8987012 Reactome:R-HSA-8987040 Reactome:R-HSA-8987042 Reactome:R-HSA-8987070 Reactome:R-HSA-8987084 Reactome:R-HSA-8987096 Reactome:R-HSA-8987129 Reactome:R-HSA-8987141 Reactome:R-HSA-8987150 Reactome:R-HSA-8987179 Reactome:R-HSA-8987202 Reactome:R-HSA-8987255 anaplastic lymphoma kinase activity ephrin-B3 receptor tyrosine kinase activity insulin receptor protein-tyrosine kinase activity molecular_function neurite outgrowth regulating kinase activity neurotrophin TRK receptor activity neurotrophin TRKA receptor activity neurotrophin TRKB receptor activity neurotrophin TRKC receptor activity novel oncogene with kinase-domain activity receptor protein tyrosine kinase activity receptor protein-tyrosine kinase activity sevenless receptor activity transmembrane receptor protein kinase activity FLT1 FLT3 KIT NTRK1 NTRK3