has_participant has participant has participant water transmembrane transporter activity water channel activity GO:0015250 RHEA:29667 Reactome:R-HSA-432010 Reactome:R-HSA-432054 Reactome:R-HSA-432065 Reactome:R-HSA-432067 Reactome:R-HSA-445714 Reactome:R-HSA-507868 Reactome:R-HSA-507870 Transport systems of this type enable facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. aquaporin molecular_function channel activity AQP1 AQP2 AQP3 AQP6