has_participant has participant has participant response to organic cyclic compound response to estradiol Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen. GO:0032355 biological_process response to E2 stimulus response to estradiol stimulus response to lipid response to oxygen-containing compound CD38 COL1A1 CRYAB PDGFRB SLC34A1 POSTN