]> execution phase of apoptosis Reactome:R-HSA-75153 execution phase of apoptotic process biological_process GO:0097194 A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. pr 2011-11-23T09:45:24Z apoptosis in taxon occurrent Schizosaccharomyces pombe has part has part has_part Opisthokonta part_of part of part of apoptotic process cellular process bleb assembly