Conotruncal defect Conotruncal heart defects A congenital malformation of the outflow tract of the heart. Conotruncal defects are thought to result from a disturbance of the outflow tract of the embryonic heart, and comprise truncus arteriosus, tetralogy of Fallot, interrupted aortic arch, transposition of the great arteries, and double outlet right ventricle. HP:0001710 human_phenotype UMLS:C1853238 Abnormal ventriculoarterial connection Congenital malformation of the great arteries