<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/KTAO?iri=http://purl.obolibrary.org/obo/HP_0003651"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:ns3="http://purl.obolibrary.org/obo/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000412"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasAlternativeId"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/BFO_0000051 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#TransitiveProperty"/>
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">has_part</rdfs:label>
        <rdfs:label>has part</rdfs:label>
        <rdfs:label xml:lang="en">has part</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000052 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000052">
        <rdf:type rdf:resource="http://www.w3.org/2002/07/owl#FunctionalProperty"/>
        <rdfs:label xml:lang="en">characteristic of</rdfs:label>
        <rdfs:label>inheres in</rdfs:label>
        <rdfs:label xml:lang="en">inheres in</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0002573 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002573">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">has modifier</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CL_0000891 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000891">
        <rdfs:label>foam cell</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0002621 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0002621">
        <rdfs:label>Atherosclerosis</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/HP_0003651 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0003651">
        <rdfs:label>Foam cells</rdfs:label>
        <equivalentClass>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
                <someValuesFrom>
                    <Class>
                        <intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0000470"/>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CL_0000891"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
                            </Restriction>
                        </intersectionOf>
                    </Class>
                </someValuesFrom>
            </Restriction>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0002621"/>
        <oboInOwl:hasExactSynonym>Presence of foam cells</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Lipid-laden histiocytes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Foamy macrophages</oboInOwl:hasExactSynonym>
        <oboInOwl:id>HP:0003651</oboInOwl:id>
        <oboInOwl:hasExactSynonym>Foamy histiocytes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>MSH:D005487</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US:16980002</oboInOwl:hasDbXref>
        <rdfs:comment>Foam cells may contain polymorphic cytoplasmic inclusions consisting of lamellar osmiophilic membranes on electron microscopy.</rdfs:comment>
        <ns3:IAO_0000115>The presence of foam cells, a type of macrophage that localizes to fatty deposits on blood vessel walls, where they ingest low-density lipoproteins and become laden with lipids, giving them a foamy appearance.</ns3:IAO_0000115>
        <oboInOwl:hasAlternativeId>HP:0003650</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>UMLS:C0016390</oboInOwl:hasDbXref>
        <ns3:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/hp.owl"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000460 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000460">
        <rdfs:label>abnormal</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PATO_0000470 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PATO_0000470">
        <rdfs:label>increased amount</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



