Abnormal anterior eye segment morphology Ocular anterior segment dysgenesis Abnormal development (dysgenesis) of the anterior segment of the eye globe. These structures are mainly of mesenchymal origin. In anterior segment mesenchymal ocular dysgenesis (ASMOD), multiple tissues are affected, including the iris, cornea, and lens as well as the Schlemm's canal and trabecular meshwork drainage structures located at the anterior segment angle where the iris and cornea meet. These abnormalities may result from a primary defect in the migration and/or differentiation of the mesenchymal cells that contribute to development of the cornea, iris, and drainage structures. Anterior segment mesencyhmal dysgenesis HP:0008040 Anterior segment developmental abnormality Anterior segment ocular dysgenesis SNOMEDCT_US:65075004 Anterior chamber mesodermal anomalies UMLS:C0266525 Anterior chamber malformation HP:0007696 HP:0007700 HP:0007699 human_phenotype Anterior chamber cleavage disorder Anterior chamber cleavage defect Anterior segment dysgenesis