Abnormal glomerular filtration rate Decreased glomerular filtration rate Impaired renal creatinine clearance Decreased GFR HP:0012213 An abnormal reduction in the volume of fluid filtered out of plasma through glomerular capillary walls into Bowman's capsules per unit of time. Reduced creatinine clearance UMLS:C0853068 HP:0000120 Renal clearance is defined as the volume of plasma per minute needed to excrete the quantity of a solute appearing in the urine in a minute. Normal values for adults are 97 to 137 ml/min (male) and 88 to 128 ml/min (female). This term refers to a reduction below normal limits in the ability of the kidney to clear creatinine from the bloodstream. 2013-03-14T07:54:30Z