Phenotypic abnormality Constitutional symptom 2016-11-29T11:02:54Z Note that we use the preferred term label constitutional symptom because this reflects common usage, but we do not restrict the term or its descendents to the narrow meaning of symptom, i.e., a complaint related by a patient to a physician. There is no generally accepted classification of what defines a constitutional symptom, but examples include weight loss, fatigue, general weakness, night sweats, shaking, chills, fever, and vomiting. A symptom or manifestation indicating a systemic or general effect of a disease and that may affect the general well-being or status of an individual. human_phenotype HP:0025142 HPO:probinson