Segmental glomerulosclerosis Tip variant segmental glomerulosclerosis 2021-01-10T13:27:31Z Segmental solidification of the glomerular tuft characterized by an adhesion at the tip of the glomerular tuft abutting the proximal tubular taek-off can be accompanied by increased extracellular matrix, causing glomerular capillary obliteration at the glomerular tip. Features including hyalinosis, foam cells, hypertrophy of overlying glomerular epithelial cells can also be observed. Segmental glomerulosclerosis, tip variant