Segmental glomerulosclerosis Segmental glomerulosclerosis away from the vascular and tubular poles 2021-01-10T13:29:02Z Segmental solidification of the glomerular tuft characterized by increased extracellular matrix, causing glomerular capillary obliteration at neirhter the tubular or vascular poles. Features including hyalinosis, foam cells, hypertrophy of overlying glomerular epithelial cells can also be observed.