disease caused by disruption of disease has basis in disruption of disease has feature aldosterone secretion Decreased circulating renin level High pulse pressure primary aldosteronism An endocrine disorder characterized by excessive production of aldosterone by the adrenal glands. Causes include adrenal gland adenoma and adrenal gland hyperplasia. The overproduction of aldosterone results in sodium and water retention and hypokalemia. Patients present with high blood pressure, muscle weakness, and headache. COHD:434000 Conn syndrome Conn's syndrome DOID:12028 Editor note: DOID class refers to adenoma-caused Conn syndrome ICD10:E26.0 ICD10:E26.01 ICD9:255.12 MONDO:0001422 NCIT:C34510 SCTID:190507007 primary aldosteronism primary hyperaldosteronism adrenal cortex adenoma adrenal gland disease