disease has basis in dysfunction of lysosome disease or disorder lysosomal storage disease A metabolic disorder caused by mutations in proteins critical for lysosomal function, including lysosomal enzymes, lysosomal integral membrane proteins, and proteins involved in the post-translational modification and trafficking of lysosomal proteins. DOID:3211 MESH:D016464 MONDO:0002561 NCIT:C61250 Orphanet:68366 SCTID:23585005 UMLS:C0085078 UMLS:CN205533 disorder of lysosomal enzyme disorder of lysosomal enzymes inborn lysosomal enzyme disorder lysosomal disease lysosomal disorder lysosomal storage disorder lysosomal storage metabolism disorder lysosome disease lysosome disorder phospholipidosis inborn errors of metabolism disease of membrane bound organelle