disease caused by disruption of disease has basis in disruption of tyrosine catabolic process inherited amino acid metabolic disorder tyrosinemia An autosomal recessive inherited metabolic disorder caused by mutations in the FAH, HPD, and TAT genes. It is characterized by deficiency of one of the enzymes that are involved in the metabolism of tyrosine. It results in elevated blood tyrosine levels and accumulation of tyrosine and its byproducts in the liver, kidney, nervous system and other organs. DOID:9275 ICD10:E70.21 ICD9:270.2 MESH:D020176 MONDO:0004741 NCIT:C98640 OMIMPS:276700 SCTID:190694001 UMLS:C0268483 disorder of tyrosine metabolism