intrinsic cardiomyopathy restrictive cardiomyopathy A type of heart disorder referring to the inability of the ventricles to fill with blood because the myocardium (heart muscle) stiffens and looses its flexibility. Causes include replacement of the myocardium with scar tissue, abnormal cellular infiltration of the myocardium, or deposition of a substance (e.g., amyloid) in the myocardium. DOID:397 EFO:0002630 ICD10:I42.5 ICD9:425.4 MESH:D002313 MONDO:0005201 MedDRA:10038748 NCIT:C62798 Orphanet:217632 SCTID:415295002 UMLS:C0007196 cardiomyopathy, constrictive familial restrictive cardiomyopathy primary restrictive cardiomyopathy restrictive cardiomyopathy