renal cell carcinoma (disease) renal cell adenocarcinoma A carcinoma arising from the renal parenchyma. There is a strong correlation between cigarette smoking and the development of renal cell carcinoma. The clinical presentation includes : hematuria, flank pain and a palpable lumbar mass. A high percentage of renal cell carcinomas are diagnosed when an ultrasound is performed for other purposes. Radical nephrectomy is the standard intervention procedure. Renal cell carcinoma is generally considered to be resistant to radiation treatment and chemotherapy. EFO:0005708 Editor note: check relationship to RCC ICDO:8311/1 ICDO:8312/3 MONDO:0005549 NCIT:C9385 RCC adenocarcinoma of kidney adenocarcinoma of the kidney carcinoma, renal cell, malignant kidney adenocarcinoma renal cell adenocarcinoma renal cell cancer renal cell carcinoma renal cell carcinoma, NOS renal cell carcinoma, stage unspecified