autosomal dominant disease Townes-Brocks syndrome DOID:0050887 GARD:0007784 ICD10:Q87.8 ICD9:759.89 MESH:C536974 MONDO:0007142 NCIT:C99085 OMIMPS:107480 Orphanet:857 SCTID:24750000 TBS TBS1 Townes syndrome Townes-Brocks syndrome Townes-Brocks syndrome (TBS) is a rare genetic disorder characterized by the triad of imperforate anus, dysplastic ears often associated with sensorineural and/or conductive hearing impairment, and thumb malformations. These features are often associated with other signs mainly affecting the kidneys and heart. Townes-Brocks syndrome 1 Townes-Brocks-branchiootorenal-like syndrome UMLS:C0265246 UMLS:CN034849 anus, imperforate, with hand, foot and ear anomalies anus, imperforate, with hand, foot, and Ear anomalies deafness, sensorineural, with imperforate anus and hypoplastic thumbs deafness, sensorineural, with imperforate anus and thumb anomalies https://rarediseases.info.nih.gov/diseases/7784/townes-brocks-syndrome imperforate anus with hand, foot and ear anomalies rear syndrome renal-Ear-anal-radial syndrome renal-ear-anal-radial syndrome sensorineural deafness with imperforate anus and hypoplastic thumbs syndromic anorectal malformation branchial arch or oral-acral syndrome otomandibular dysplasia associated with monogenic syndromes syndromic urogenital tract malformation syndrome with limb duplication, polydactyly, syndactyly, and/or hyperphalangy genetic otorhinolaryngologic disease syndromic genetic deafness syndromic renal or urinary tract malformation genetic multiple congenital anomalies/dysmorphic syndrome without intellectual disability