disease has basis in dysfunction of FLCN autosomal dominant disease Birt-Hogg-Dube syndrome BHD BHD syndrome Birt Hogg Dube syndrome Birt-Hogg-Dube (BHD) syndrome is characterized by skin lesions, kidney tumors, and pulmonary cysts that may be associated with pneumothorax. It is a rare clinicopathologic condition named after the three Canadian physicians who reported the syndrome in 1977. Birt-Hogg-Dube syndrome Birt-Hogg-Dubé syndrome DOID:0050676 EFO:1001273 GARD:0002322 Hornstein-Knickenberg syndrome ICD9:704.8 MESH:D058249 MONDO:0007607 MedDRA:10067736 NCIT:C28244 OMIM:135150 Orphanet:122 SCTID:110985001 UMLS:C0346010 fibrofolliculomas with trichodiscomas and acrochordons inherited skin tumor inherited renal cancer-predisposing syndrome kidney neoplasm