lupus erythematosus systemic lupus erythematosus (disease) An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific. COHD:257628 DOID:9074 EFO:0002690 HP:0002725 ICD10:M32 ICD10:M32.0 ICD10:M32.1 ICD10:M32.8 ICD10:M32.9 ICD9:710.0 KEGG:05322 MESH:D008180 MONDO:0007915 NCIT:C3201 OMIM:152700 Orphanet:536 SCTID:55464009 SLE SLE - lupus erythematosus, systemic disseminated lupus erythematosus excess LMW-DNA excess lymphocyte low molecular weight DNA lupus erythematosus, systemic systemic lupus erythematosus systemic autoimmune disease secondary glomerular disease thrombotic microangiopathy