severe pre-eclampsia syndromic disease HELLP syndrome DOID:13133 EFO:0007297 GARD:0008528 HELLP syndrome is a life-threatening condition that can potentially complicate pregnancy. It is named for 3 features of the condition: H emolysis, E levated L iver enzyme levels, and L ow P latelet levels. It typically occurs in the last 3 months of pregnancy (the third trimester) but can also start soon after delivery. A wide range of non-specific symptoms may be present in women with HELLP syndrome. Symptoms may include fatigue; malaise; fluid retention and excess weight gain; headache; nausea and vomiting; pain in the upper right or middle of the abdomen; blurry vision; and rarely, nosebleed or seizures. The cause of HELLP syndrome is not known, but certain risk factors have been associated with the condition. It is most common in women with preeclampsia or eclampsia. If not diagnosed and treated quickly, HELLP syndrome can lead to serious complications for the mother and baby.The main treatment is to deliver the baby as soon as possible, even if premature. Treatment may also includemedications needed for the mother or baby, and blood transfusion for severe bleeding problems. ICD10:O14.2 MESH:D017359 MONDO:0008585 MedDRA:10049058 NCIT:C84750 OMIM:189800 Orphanet:244242 PEE1 PREECLAMPSIA/eclampsia 1 Preg1 UMLS:C0162739 hemolysis, elevated liver enzymes, and Low Platelet count hemolysis, elevated liver enzymes, low platelets in pregnancy hemolysis, elevated liver enzymes, lowered platelets hemolysis-elevated liver enzymes-Low Platelet count syndrome hemolysis-elevated liver enzymes-low platelets syndrome https://rarediseases.info.nih.gov/diseases/8528/hellp-syndrome hypertension, pregnancy-induced pee toxemia of pregnancy hemorrhagic disorder due to an acquired platelet anomaly