disease has basis in dysfunction of NLRP3 autosomal dominant disease Muckle-Wells syndrome Cryopyrin-associated periodic syndrome 2 DOID:0050854 GARD:0008472 ICD10:E85.0 ICD9:708.8 MONDO:0008633 MUCKLE-Wells syndrome MWS MedDRA:10064569 Muckle Wells syndrome Muckle-Wells syndrome Muckle-Wells syndrome (MWS) is an intermediate form of cryopyrin-associated periodic syndrome (CAPS) and is characterized by recurrent fever (with malaise and chills), recurrent urticaria-like skin rash, sensorineural deafness, general signs of inflammation (eye redness, headaches, arthralgia/myalgia) and potentially life-threatening secondary amyloidosis (AA type). NCIT:C119054 OMIM:191900 Orphanet:575 SCTID:402417009 UMLS:C0268390 UMLS:C1304205 Uda syndrome neutrophilic urticaria urticaria, deafness and amyloidosis urticaria-deafness-amyloidosis syndrome cryopyrin-associated periodic syndrome secondary glomerular disease