disease has basis in dysfunction of disease has feature TREX1 autoimmune disease of cardiovascular system retinal vascular disease retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations ADRVCL CRV DOID:0111567 Editor note: Orphanet:3421 is obsolete in the 2017 edition of ORDO, but the Orphanet website shows as active, see https://github.com/Orphanet/ORDO/issues/1 GARD:0001217 GARD:0002558 GARD:0010535 HVR MESH:C566007 MONDO:0008641 OMIM:192315 Orphanet:247691 RVCL RVCL-S Retinal vasculopathy and cerebral leukodystrophy (RVCL) is an inherited group of small vessel diseases comprised of cerebroretinal vasculopathy (CRV), hereditary vascular retinopathy (HRV) and hereditary endotheliopathy with retinopathy, nephropathy and stroke (HERNS); all exhibiting progressive visual impairment as well as variable cerebral dysfunction. SCTID:720854004 SCTID:721141004 UMLS:C1860518 autosomal dominant retinal vasculopathy with cerebral leukodystrophy cerebroretinal vasculopathy cerebroretinal vasculopathy, hereditary grand Kaine fulling syndrome grand-Kaine-fulling syndrome hereditary vascular retinopathy https://rarediseases.info.nih.gov/diseases/10535/hereditary-vascular-retinopathy https://rarediseases.info.nih.gov/diseases/1217/retinal-vasculopathy-with-cerebral-leukodystrophy https://rarediseases.info.nih.gov/diseases/2558/grand-kaine-fulling-syndrome retinal vasculopathy and cerebral leukoencephalopathy retinal vasculopathy with cerebral leukodystrophy retinopathy, vascular, with cerebral and renal involvement and Raynaud and migraine phenomena vasculopathy, retinal, with cerebral leukodystrophy systemic autoimmune disease genetic otorhinolaryngologic disease type 1 interferonopathy genetic cerebral small vessel disease inherited retinal dystrophy disease of glomerular basement membrane autoimmune retinopathy