cloacal exstrophy (disease) Cloacal exstrophy (EC) is a major birth defect representing the severe end of the spectrum of the exstrophy-epispadias complex (EEC) characterized by omphalocele, exstrophy, imperforate anus and spinal defects (also referred to as the OEIS complex), often associated with other malformations. DOID:0080175 GARD:0004080 HP:0010475 ICD10:Q64.1 ICD9:759.89 MESH:C537748 MONDO:0009774 MedDRA:10067424 NCIT:C99142 OEIS complex OEIS syndrome OMIM:258040 Orphanet:93929 SCTID:20815007 UMLS:C1850321 cloacal exstrophy cloacal exstrophy sequence omphalocele - cloacal exstrophy - imperforate anus - spinal defect omphalocele, exstrophy of the cloaca, imperforate anus, and spinal defects omphalocele, exstrophy of the cloaca, imperforate anus, and spinal defects complex omphalocele-cloacal exstrophy-imperforate anus-spinal defect syndrome omphalocele-exstrophy-imperforate anus-spinal defects syndromic diaphragmatic or abdominal wall malformation syndromic anorectal malformation syndromic urogenital tract malformation bladder exstrophy-epispadias-cloacal exstrophy complex